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1

Enzymatic Synthesis of Amoxicillin via a One-pot Enzymatic Hydrolysis and Condensation Cascade Process in the Presence of Organic Co-solvents

Qi Wu, Chun-Xiu Chen, Li-Li Du, Xian-Fu Lin

Journal:

Applied Biochemistry and Biotechnology

Year:

2010

Language:

english

File:

PDF, 214 KB

english, 2010

2

A Combination of Computational and Experimental Approaches to Investigate the Binding Behavior of B.sub Lipase A Mutants with Substrate pNPP

Zhong Ni, Xin Jin, Peng Zhou, Qi Wu, Xian-Fu Lin

Journal:

Molecular Informatics

Year:

2011

Language:

english

File:

PDF, 546 KB

english, 2011

3

Anhydrous tert-pentanol as a novel media for the efficient enzymatic synthesis of amoxicillin

Chun-Xiu Chen, Qi Wu, Bo-Kai Liu, De-Shui Lv, Xian-Fu Lin

Journal:

Enzyme and Microbial Technology

Year:

2008

Language:

english

File:

PDF, 356 KB

english, 2008

4

Bovine serum albumin-catalyzed one-pot synthesis of 2-aminothiophenes via Gewald reaction

Zhao, Dan-Dan, Li, Li, Xu, Fan, Wu, Qi, Lin, Xian-Fu

Journal:

Journal of Molecular Catalysis B: Enzymatic

Year:

2013

Language:

english

File:

PDF, 2.57 MB

english, 2013

5

Enzymatic enantioselective aldol reactions of isatin derivatives with cyclic ketones under solvent-free conditions

Liu, Zhi-Qiang, Xiang, Zi-Wei, Shen, Zhou, Wu, Qi, Lin, Xian-Fu

Journal:

Year:

2014

Language:

english

File:

PDF, 867 KB

english, 2014

6

Promiscuous Acylases-Catalyzed Markovnikov Addition of N-Heterocycles to Vinyl Esters in Organic Media

Wei-Bo Wu, Jian-Ming Xu, Qi Wu, De-Shui Lv, Xian-Fu Lin

Journal:

Advanced Synthesis & Catalysis

Year:

2006

Language:

english

File:

PDF, 92 KB

english, 2006

7

Candida antarctica Lipase B (CAL-B)-Catalyzed Carbon-Sulfur Bond Addition and Controllable Selectivity in Organic Media

Feng-Wen Lou, Bo-Kai Liu, Qi Wu, De-Shui Lv, Xian-Fu Lin

Journal:

Advanced Synthesis & Catalysis

Year:

2008

Language:

english

File:

PDF, 161 KB

english, 2008

8

Promiscuous Zinc-Dependent Acylase-Mediated One-Pot Synthesis of Monosaccharide-Containing Pyrimidine Derivatives in Organic Medium

Qi Wu, Jian-Ming Xu, Li Xia, Jun-Liang Wang, Xian-Fu Lin

Journal:

Advanced Synthesis & Catalysis

Year:

2009

Language:

english

File:

PDF, 242 KB

english, 2009

9

Graft copolymerization of water-soluble monomers containing quaternary ammonium group on poly(vinyl alcohol) using ceric ions

San-Yan Zheng, Zhi-Chun Chen, De-Shui Lu, Qi Wu, Xian-Fu Lin

Journal:

Journal of Applied Polymer Science

Year:

2005

Language:

english

File:

PDF, 89 KB

english, 2005

10

Chemoenzymatic synthesis, characterization, and controlled release of functional polymeric prodrugs with acyclovir as pendant

Xia Li, Qi Wu, Fu Zhang, Xian-Fu Lin

Journal:

Journal of Applied Polymer Science

Year:

2008

Language:

english

File:

PDF, 295 KB

english, 2008

11

Synthesis and characterization of saccharide-functionalized polymer–gemcitabine conjugates based on chemoenzymatic selective strategy

Guo-Jun Zhou, Xia Li, Ming-Xing Teng, Guo-Hai Chu, Xian-Fu Lin

Journal:

Journal of Applied Polymer Science

Year:

2012

Language:

english

File:

PDF, 1.01 MB

english, 2012

12

Alkaline Protease from Bacillus subtilis Catalyzed Michael Addition of Pyrimidine Derivatives to α,β-Ethylenic Compounds in Organic Media.

Ying Cai, Xiao-Feng Sun, Na Wang, Xian-Fu Lin

Journal:

Year:

2004

File:

PDF, 99 KB

2004

13

Penicillin G Acylase Catalyzed Markovnikov Addition of Allopurinol to Vinyl Ester.

Wei-Bo Wu, Na Wang, Jian-Ming Xu, Qi Wu, Xian-Fu Lin

Journal:

Year:

2005

File:

PDF, 14 KB

2005

14

D-Aminoacylase-Catalyzed Markovnikov Addition of Azoles to Vinyl Esters in Organic Solvents.

Wei-Bo Wu, Jian-Ming Xu, Qi Wu, De-Shui Lv, Xian-Fu Lin

Journal:

Year:

2006

File:

PDF, 17 KB

2006

15

ChemInform Abstract: Promiscuous Enzyme-Catalyzed Regioselective Michael Addition of Purine Derivatives to α,β-Unsaturated Carbonyl Compounds in Organic Solvent.

Jun-Liang Wang, Jian-Ming Xu, Qi Wu, De-Shui Lv, Xian-Fu Lin

Journal:

Year:

2009

File:

PDF, 38 KB

2009

16

ChemInform Abstract: Acidic Ionic Liquid [NMP]H2PO4 as Dual Solvent-Catalyst for Synthesis of β-Alkoxyketones by the Oxa-Michael Addition Reactions.

Hui Guo, Xia Li, Jun-Liang Wang, Xiao-Han Jin, Xian-Fu Lin

Journal:

Year:

2011

File:

PDF, 40 KB

2011

17

ChemInform Abstract: Facile Multicomponent Synthesis of Novel 2,3-Dihydropyran Derivatives under Solvent-Free Conditions.

Li Li, Qi Wu, Bo-Kai Liu, Xian-Fu Lin

Journal:

Year:

2011

File:

PDF, 46 KB

2011

18

ChemInform Abstract: Candida antarctica Lipase B-Catalyzed the Unprecedented Three-Component Hantzsch-Type Reaction of Aldehyde with Acetamide and 1,3-Dicarbonyl Compounds in Non-Aqueous Solvent.

Jun-Liang Wang, Bo-Kai Liu, Cui Yin, Qi Wu, Xian-Fu Lin

Journal:

Year:

2011

File:

PDF, 28 KB

2011

19

A Basic Ionic Liquid as Catalyst and Reaction Medium: A Rapid and Simple Procedure for Aza-Michael Addition Reactions

Jian-Ming Xu, Qi Wu, Qing-Yi Zhang, Fu Zhang, Xian-Fu Lin

Journal:

European Journal of Organic Chemistry

Year:

2007

Language:

english

File:

PDF, 109 KB

english, 2007

20

Immobilization of penicillin G acylase on a composite carrier with a biocompatible microenvironment of chitosan

Xin Jin, Qi Wu, Qing Chen, Chun-Xiu Chen, Xian-Fu Lin

Journal:

Journal of Chemical Technology & Biotechnology

Year:

2008

Language:

english

File:

PDF, 176 KB

english, 2008

21

Chemo-Enzymatic Synthesis of Raffinose-Branched Polyelectrolytes and Self-Assembly Application in Microcapsules

Qi Wu, Zhi-Chun Chen, De-Shui Lu, Xian-Fu Lin

Journal:

Macromolecular Bioscience

Year:

2006

Language:

english

File:

PDF, 149 KB

english, 2006

22

Design and in vitro Biodegradation of Novel Hepatocyte-Targetable (Galactose Polycation/Hemoglobin) Multilayers and Microcapsules

Fu Zhang, Li-Jun Liu, Qi Wu, Xian-Fu Lin

Journal:

Macromolecular Chemistry and Physics

Year:

2009

Language:

english

File:

PDF, 696 KB

english, 2009

23

Controllable synthesis of polymerizable ester and amide prodrugs of acyclovir by enzyme in organic solvent

Xia Li, Qi Wu, De-shui Lv, Xian-fu Lin

Journal:

Bioorganic & Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 156 KB

english, 2006

24

Thermal treatment of galactose-branched polyelectrolyte microcapsules to improve drug delivery with reserved targetability

Fu Zhang, Qi Wu, Li-Jun Liu, Zhi-Chun Chen, Xian-Fu Lin

Journal:

International Journal of Pharmaceutics

Year:

2008

Language:

english

File:

PDF, 1.69 MB

english, 2008

25

Facile synthesis of novel mutual derivatives of nucleosides and pyrimidines by regioselectively chemo-enzymatic protocol

Xueqi Qian, Bokai Liu, Qi Wu, Deshui Lv, Xian-Fu Lin

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 180 KB

english, 2008

26

Chemo-enzymatic synthesis of disaccharide-branched copolymers with high molecular weight

Xu Wang, Qi Wu, Na Wang, Xian-Fu Lin

Journal:

Carbohydrate Polymers

Year:

2005

Language:

english

File:

PDF, 171 KB

english, 2005

27

Regioselective monoacylation of cyclomaltoheptaose at the C-2 secondary hydroxyl groups by the alkaline protease from Bacillus subtilis in nonaqueous media

Yong-mei Xiao, Qi Wu, Na Wang, Xian-fu Lin

Journal:

Carbohydrate Research

Year:

2004

Language:

english

File:

PDF, 281 KB

english, 2004

28

Ultrasound-accelerated enzymatic synthesis of sugar esters in nonaqueous solvents

Yong-mei Xiao, Qi Wu, Ying Cai, Xian-fu Lin

Journal:

Carbohydrate Research

Year:

2005

Language:

english

File:

PDF, 166 KB

english, 2005

29

Synthesis and characterization of drug–saccharide conjugates by enzymatic strategy in organic media

Jing Quan, Jian-Ming Xu, Bo-Kai Liu, Cheng-Zhen Zheng, Xian-Fu Lin

Journal:

Enzyme and Microbial Technology

Year:

2007

Language:

english

File:

PDF, 624 KB

english, 2007

30

Hydrolase-catalyzed fast Henry reaction of nitroalkanes and aldehydes in organic media

Jun-Liang Wang, Xia Li, Hong-Yan Xie, Bo-Kai Liu, Xian-Fu Lin

Journal:

Journal of Biotechnology

Year:

2010

Language:

english

File:

PDF, 247 KB

english, 2010

31

Hepatic-targeting microcapsules construction by self-assembly of bioactive galactose-branched polyelectrolyte for controlled drug release system

Fu Zhang, Qi Wu, Zhi-Chun Chen, Ming Zhang, Xian-Fu Lin

Journal:

Journal of Colloid and Interface Science

Year:

2008

Language:

english

File:

PDF, 545 KB

english, 2008

32

Multidrug nanoparticles based on novel random copolymer containing cytarabine and fluorodeoxyuridine

Cui Yin, Xia Li, Qi Wu, Jun-Liang Wang, Xian-Fu Lin

Journal:

Journal of Colloid and Interface Science

Year:

2010

Language:

english

File:

PDF, 476 KB

english, 2010

33

Synthesis of polymeric prodrugs of chlorphenesin with saccharide branches by chemo-enzymatic regioselective strategy

Jing Quan, Qi Wu, Xian-Fu Lin

Journal:

Year:

2007

Language:

english

File:

PDF, 373 KB

english, 2007

34

Regioselective synthesis of amphiphilic metoprolol–saccharide conjugates by enzymatic strategy in organic media

Cheng-Zhen Zheng, Jun-Liang Wang, Xia Li, Bo-Kai Liu, Qi Wu, Xian-Fu Lin

Journal:

Process Biochemistry

Year:

2011

Language:

english

File:

PDF, 225 KB

english, 2011

35

A fast and highly efficient protocol for Michael addition of N-heterocycles to α,β-unsaturated compound using basic ionic liquid [bmIm]OH as catalyst and green solvent

Jian-Ming Xu, Chao Qian, Bo-Kai Liu, Qi Wu, Xian-Fu Lin

Journal:

Year:

2007

Language:

english

File:

PDF, 664 KB

english, 2007

36

Promiscuous enzyme-catalyzed regioselective Michael addition of purine derivatives to α,β-unsaturated carbonyl compounds in organic solvent

Jun-Liang Wang, Jian-Ming Xu, Qi Wu, De-Shui Lv, Xian-Fu Lin

Journal:

Year:

2009

Language:

english

File:

PDF, 533 KB

english, 2009

37

Acidic ionic liquid [NMP]H2PO4 as dual solvent-catalyst for synthesis of β-alkoxyketones by the oxa-Michael addition reactions

Hui Guo, Xia Li, Jun-Liang Wang, Xiao-Han Jin, Xian-Fu Lin

Journal:

Year:

2010

Language:

english

File:

PDF, 2.18 MB

english, 2010

38

Candida antarctica lipase B-catalyzed the unprecedented three-component Hantzsch-type reaction of aldehyde with acetamide and 1,3-dicarbonyl compounds in non-aqueous solvent

Jun-Liang Wang, Bo-Kai Liu, Cui Yin, Qi Wu, Xian-Fu Lin

Journal:

Year:

2011

Language:

english

File:

PDF, 224 KB

english, 2011

39

A novel and highly efficient protocol for Markovnikov’s addition using ionic liquid as catalytic green solvent

Jian-Ming Xu, Wei-Bo Wu, Chao Qian, Bo-Kai Liu, Xian-Fu Lin

Journal:

Tetrahedron Letters

Year:

2006

Language:

english

File:

PDF, 102 KB

english, 2006

40

Promiscuous acylase-catalyzed aza-Michael additions of aromatic N-heterocycles in organic solvent

Chao Qian, Jian-Ming Xu, Qi Wu, De-Shui Lv, Xian-Fu Lin

Journal:

Tetrahedron Letters

Year:

2007

Language:

english

File:

PDF, 148 KB

english, 2007

41

Highly selective anti-Markovnikov addition of thiols to vinyl ethers under solvent- and catalyst-free conditions

Feng-Wen Lou, Jian-Ming Xu, Bo-Kai Liu, Qi Wu, Qian Pan, Xian-Fu Lin

Journal:

Tetrahedron Letters

Year:

2007

Language:

english

File:

PDF, 128 KB

english, 2007

42

Novel designed polymer–acyclovir conjugates with linker-controlled drug release and hepatoma cell targeting

Xia Li, Min Lu, Qi Wu, De-shui Lv, Xian-Fu Lin

Journal:

Journal of Polymer Science Part A: Polymer Chemistry

Year:

2008

Language:

english

File:

PDF, 351 KB

english, 2008

43

Novel mutual pro-drugs of 2′,3′-dideoxyinosine with 3-octadecyloxy-propane-1,2-diol by straightforward enzymatic regioselective synthesis in acetone

Xiao-Feng Sun, Qi Wu, Na Wang, Ying Cai, Xian-Fu Lin

Journal:

Biotechnology Letters

Year:

2005

Language:

english

File:

PDF, 258 KB

english, 2005

44

Controllable Regioselective Acylation of Rutin Catalyzed by Enzymes in Non-aqueous Solvents

Yong-mei Xiao, Qi Wu, Wei-bo Wu, Qing-yi Zhang, Xian-fu Lin

Journal:

Biotechnology Letters

Year:

2005

Language:

english

File:

PDF, 202 KB

english, 2005

45

Regioselective enzymatic acylation of ribavirin to give potential multifunctional derivatives

Bo-Kai Liu, Na Wang, Qi Wu, Chuan-Ying Xie, Xian-Fu Lin

Journal:

Biotechnology Letters

Year:

2005

Language:

english

File:

PDF, 196 KB

english, 2005

46

A Facile Method for Preparation of Polymerizable, Optically Active Ketoprofen Prodrug by Irreversible Lipase-catalysed Resolution

Xiao-Qing Cai, Zhi-Chun Chen, Na Wang, Xian-Fu Lin

Journal:

World Journal of Microbiology and Biotechnology

Year:

2006

Language:

english

File:

PDF, 211 KB

english, 2006

47

Regiospecific alkaline protease-catalyzed divinyl acyl transesterifications of primary hydroxyl groups of mono- and di-saccharides in pyridine

Qi Wu, Na Wang, Yong-Mei Xiao, De-Shui Lu, Xian-Fu Lin

Journal:

Carbohydrate Research

Year:

2004

Language:

english

File:

PDF, 349 KB

english, 2004

48

Chemo-enzymatic synthesis and sustained release of optically active polymeric prodrugs of chlorphenesin

Jing Quan, Qi Wu, Li-Min Zhu, Xian-Fu Lin

Journal:

Year:

2008

Language:

english

File:

PDF, 282 KB

english, 2008

49

Integrating In Silico and In vitro Approaches to Dissect the Stereoselectivity of Bacillus subtilis Lipase A toward Ketoprofen Vinyl Ester

Zhong Ni, Peng Zhou, Xin Jin, Xian-Fu Lin

Journal:

Chemical Biology & Drug Design

Year:

2011

Language:

english

File:

PDF, 282 KB

english, 2011

50

Pepsin nanofilm self-assembly on the positively charged poly (ethylene terephthalate) substrate

Xu Li-heng, Chen Zhi-chun, Li Yang-mei, Lu De-shui, Lin Xian-fu, Yuan Jun

Journal:

Journal of Zhejiang University SCIENCE A

Year:

2002

Language:

english

File:

PDF, 468 KB

english, 2002

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